经皮内镜椎间孔入路微创治疗腰椎间盘突出症疗效的meta分析

Meta-analysis of percutaneous endoscopic transforaminal lumbar discectomy in curative effect of minimally invasive treatment of lumbar disc herniation

摘要:

目的 本研究通过meta分析评估经皮内镜椎间孔入路微创手术（PETFA）治疗腰椎间盘突出症的疗效，为临床提供科学依据。方法 检索PubMed、EMbase、Web of Science、CNKI和万方数据库，筛选随机对照试验（RCTs），使用Rev Man 5.3软件，采用相对风险（RR）和标准化平均差异（SMD）进行统计。结果 纳入8篇高质量研究，涉及462例患者。结果显示PETFA手术的多项指标均优于传统手术，包括更短的手术时间［平均差（MD）=-6.51］，较少的术中出血（MD=-7.09），更短的住院时间（MD=-2.85），以及更佳的术后疼痛缓解（MD=-1.68）和功能恢复（MD=-0.89）。结论 PETFA微创手术在治疗腰椎间盘突出症方面具显著优势，推荐在临床中广泛应用。

Abstract:

Objective Using a meta-analysis to evaluate the effectiveness of percutaneous endoscopic transforaminal lumbar discectomy (PETFA) in treating lumbar disc herniation, inorder to provide a scientific basis for clinical practice.Methods We searched databases such as PubMed, EMbase, Web of Science, CNKI, and Wanfang, selecting randomized controlled trials (RCTs). Statistical analyses were conducted using RevMan 5.3 software, employing relative risk (RR) and standardized mean difference (SMD).Results Eight high-quality studies involving 462 patients were included. The findings demonstrate that PETFA surgery significantly outperforms traditional surgery in various metrics, including shorter surgery duration (MD=-6.51), reduced intraoperative blood loss (MD=-7.09), shorter hospital stays (MD=-2.85), improved postoperative pain relief (MD=-1.68), and enhanced functional recovery (MD=-0.89).Conclusion PETFA minimally invasive surgery exhibits significant advantages in treating lumbar disc herniation, making it highly recommended for widespread clinical use.