女性中医体质辨识与人流术后宫腔粘连形成的相关性研究

Correlation between female traditional Chinese medicine constitution and uterine adhesions after abortion

摘要:

目的 通过病例对照调查研究，探讨宫腔粘连（IUA）患者易感中医体质类型及发病相关的危险因素。方法 选取2021年9月1日至2023年1月31日在衡阳县妇幼保健院行人流术后发生IUA的患者作为IUA组，同期行人流术但未发生粘连者作为非IUA组。通过问卷调查方式收集所纳入的对象的一般资料和中医体质调查问卷，将资料进行统计整理。应用统计学方法分析比较两组的中医体质类型差异及相关的危险因素，所得数据进行二元Logistic回归分析。结果 两组患者在是否有宫腔手术史（P=0.017）和是否为痰湿体质（P=0.027）方面比较差异有统计学意义（P<0.05），在年龄、体重指数、分娩次数、经期时间、月经量、其余体质等方面比较差异无统计学意义（P>0.05）。IUA组既往妊娠次数高于非IUA组（t=-2.804，P=0.006），人流术后月经周期（t=2.550，P=0.011）和经期时间（t=8.027，P=0.000）均短于非IUA组。二元Logistic回归分析显示IUA相关危险因素为：既往宫腔手术史［回归系数值为0.598，优势比（O^R值）为1.818］、痰湿质的回归系数值［回归系数值为1.091，优势比（O^R值）为2.977］。结论 既往妊娠次数和宫腔手术史是IUA发生的高危因素，痰湿质是其发生的中医易感体质。

关键词:宫腔粘连;中医体质;痰湿质;危险因素

Abstract:

Objective To investigate the types of traditional Chinese medicine constitution susceptible to patients with intrauterine adhesions and the correlation of morbidity through case-control investigation.Methods In this study, patients with intrauterine adhesions after abortion in Hengyang County Maternal and Child Health Hospital from September 1, 2021 to January 31, 2023 were selected as intrauterine adhesion (IUA) group, and those who underwent abortion during the same period without adhesions were selected as non-IUA group. General data and traditional Chinese medicine physique questionnaire were collected by means of questionnaire, and the data were sorted out statistically. Statistical methods were used to analyze and compare the differences of traditional Chinese medicine (TCM) physique types and related risk factors between the two groups, and binary Logistic regression analysis was performed on the data obtained.Results There were statistical differences between the two groups in the history of uterine surgery (P=0.017) and phlegm-damp constitution (P=0.027). There were no statistical differences in age, body mass index, delivery frequency, menstrual duration, menstrual volume and other physical constitution (P<0.05). The number of previous pregnancies (t=-2.804, P=0.006), menstrual cycle (t=2.550, P=0.011) and menstrual duration (t=8.027, P=0.000) in IUA group were shorter than those in non-IUA group, and the difference was statistically significant. Binary Logistic regression analysis showed that the risk factors related to uterine adhesion were: previous history of uterine surgery [regression coefficient value was 0.598, odds ratio (O^R value) was 1.818] and regression coefficient value of phlegm-dampness [regression coefficient value was 1.091, odds ratio (O^R value) was 2.977].Conclusion The number of previous pregnancies and history of uterine operation are the high risk factors of uterine adhesions, and phlegm and dampness are the susceptible constitution of Chinese medicine.

Key words:intrauterine adhesion;traditional Chinese medicine constitution;phlegm and dampness;risk factor