Abstract:Objective To explore and analyze the effectiveness of total hip arthroplasty through the posterior lateral approach and direct anterior approach in the treatment of femoral head necrosis and its impact on trauma response.Methods From April 2020 to April 2023, 60 patients with femoral head necrosis who underwent total hip arthroplasty in Luoyang Orthopedic-Traumatological Hospital of Henan Province were randomly divided into two groups: the posterior lateral approach group and the direct approach group, with 30 cases each. The surgical treatment status of the two groups was compared and analyzed.Results The incision length of the direct anterior approach group was shorter than that of the posterior lateral approach group, with less intraoperative bleeding and postoperative drainage volume. The postoperative drainage time and hospitalization time of the direct anterior approach group were shorter than those of the posterior lateral approach group (P<0.05). The C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels in the direct anterior approach group were lower than those in the posterior lateral approach group 1 day after surgery (P<0.05). At 1 month, 3 months, and 6 months after surgery, the Visual Analogue Scale (VAS) score of the direct anterior approach group was lower than that of the posterior lateral approach group, and the hip joint function (Harris) score was higher than that of the posterior lateral approach group (P<0.05). There was no significant difference in the incidence of postoperative complications between the two groups (P>0.05).Conclusion Total hip arthroplasty using two different approaches for the treatment of femoral head necrosis is safe and effective. However, the direct anterior approach can reduce trauma, shorten recovery time, reduce trauma reactions, and promote functional recovery, which is worth promoting.