早期神经介入对颅内动脉瘤破裂预后及神经功能的影响

Effect of early nerve intervention on prognosis and nerve function of ruptured intracranial aneurysms

摘要:

目的 分析早期神经介入对颅内动脉瘤破裂预后及神经功能的影响。方法 将2019年7月至2023年8月鹤壁市人民医院收治的83例颅内动脉瘤破裂患者分为试验组42例与对照组41例，两组均给予神经介入栓塞术治疗，试验组选择在发病24 h内进行手术，对照组选择在发病72~96 h进行手术。结果 试验组术后基质金属蛋白酶-9（MMP-9）、神经元特异性烯醇化酶（NSE）、髓鞘碱性蛋白（MBP）水平显著低于对照组，术后各项生活质量评分高于对照组，术后并发症发生率低于对照组，预后情况优于对照组（P<0.05）。结论 早期神经介入可提高颅内动脉瘤破裂患者的神经功能，提高患者的预后。

Abstract:

Objective To analyze the effect of early nerve intervention on the prognosis and nerve function of ruptured intracranial aneurysms.Methods Eighty-three patients with ruptured intracranial aneurysms in the People's Hospital of Hebi were divided into experimental group (42 cases) and control group (41 cases). Both groups were treated with nerve interventional embolization. The operation was performed within 24 hours in the experimental group and 72 to 96 hours in the control group.Results The levels of matrix metalloproteinase 9 (MMP-9), neuron-specific enolase (NSE) and myelin basic protein (MBP) in the experimental group were significantly lower than those in the control group, the scores of quality of life in the experimental group were higher than those in the control group, the incidence of postoperative complications in the experimental group was lower than that in the control group, and the prognosis in the experimental group was better than that in the control group, with significant differences between the groups (P<0.05).Conclusion Early nerve intervention can improve the neurological function and prognosis of patients with ruptured intracranial aneurysm.