Abstract:【Objective】To explore the significance and value of different vertebral morphological changes in the diagnosis of diseases by X-ray,CT and MRI.【Methods】From March 2018 to April 2020,301 patients with vertebral body shape changes were selected as the study objects.The clinical characteristics,imaging,pathological data were retrospectively analyzed and relevant special case literature were reviewed.【Results】Among the 301 patients,there were acute cuneiform changes(98 compression fractures),acute endplate bending(52 compression fractures),chronic local defect of endplate(80 Schmorl's nodules),chronic anterior edge local separation(vertebra marginal bone)in 13,square vertebra,bamboo vertebra(10 ankylosing spondylitis),double concave vertebra(fish mouth vertebra)in 25,hemivertebra deformity,butterfly vertebra in 5,fusion vertebra in 2,10 cases of vertebral vertical palisade(hemangioma),3 cases of vertebral lipoma,and 3 cases of vertebral sandwich(osteopetrosis).In the literature of special cases,there were flattened vertebrae,downward bird's beak like change(Hurler's syndrome,mucopolysaccharide type I)in the front of vertebrae,stepped central impression of endplate(H-shaped vertebrae)-sickle cell anemia;multiple fanshaped changes(neurofibromatosis)in the posterior margin of vertebrae,vertebral frame syndrome with coarse bone trabecula(peget's disease),rugby strip syndrome(hyperparathyroidism).【Conclusion】In the process of image examination,by observing the shape change of vertebral body,it can help to judge the classification of some diseases and provide more paths for clinical diagnosis.
