阿奇霉素联合阿希米治疗女性生殖道沙眼衣原体感染的研究

Observation of effects on treatment of female genital infection by chlamydia trachomatis with Azithromycin and Asimi

摘要:

目的探讨阿奇霉素联合阴道应用阿希米治疗女性生殖道沙眼衣原体感染的疗效,并与单纯阿奇霉素治疗组进行比较.方法将96例定量PCR法检测沙眼衣原体阳性的患者随机分为两组,治疗组50例用阿奇霉素联合阴道应用阿希米治疗,对照组46例单纯应用阿奇霉素治疗.结果阿奇霉素联合阴道应用阿希米组痊愈47例(94%),显效2例(4%),有效1例(2%),有效率100%;单纯用阿奇霉素治疗组痊愈30例(65.2%),显效7例(15.2%),有效5例(10.9%),无效4例(8.7%),有效率91.3%,两组有效率比较有显著性差异(P＜0.05).结论阿奇霉素联合阴道应用阿希米治疗女性生殖道沙眼衣原体感染较单纯阿奇霉素治疗效果更佳,是临床治疗女性生殖道沙眼衣原体感染的一种极有价值的方法.

Abstract:

Objective: To investigate the efficiency of Azitromycin and Asimi in female genital infection by chlamydia trachomatis(CT). Methods: 96 fluorescence Polymerase Chain Reaction (PCR)-positive patients were divided into two groups randomly. The test group of 50 cases were given Asimi in genital duct and Azitromyxin. The control group of 46 cases were only given Azitromyxin. Results: In the test group, 47 cases (94%) were cured, 2 cases (4%) responded to the preparation, 1 case (2%) was effected and the effective rate was 100%; In the control group, 30 cases (65.2%) were cured, 7 cases (15.2%) responded to the preparation, 5 cases (10.9%) were effected and the effective rate was 91.3%. The difference of the two effective rate had statistical significance (P<0.05). Conclusion: In the treatment of chlamydia trachomatis, Asimi in genital duct and Azitromyxin are more effiective than Azitromyxin only and it is worthwhile in the treatment of female genital infection by CT.