甲氰咪胍与硫糖铝对老年食管癌术后院内感染性肺炎的观察

Effect of sucralfate and cimetidine on hodoromisl pneumonia in aged patients with esophageal cancer

摘要:

目的观察甲氰咪胍与硫糖铝对老年食管癌术后院内感染性肺炎的影响.方法将60岁以上食管癌病人分为甲氰咪胍组、硫糖铝组、对照组,术后观察院内感染性肺炎情况.结果院内感染性肺炎发生率:甲氰咪胍组30.6%,硫糖铝组8.6%,对照组10.7%,甲氰咪胍组分别与硫糖铝组、对照组相比,差别有统计学意义.硫糖铝组与对照组相比,差別无统计学意义.结论甲氰咪胍组与硫糖铝组相比,可引起较高的院内感染肺炎的发生率,硫糖铝在老年食管癌病人术后可替代甲氰咪胍应用.

关键词:院内感染性肺炎;食管癌;H2受体阻滞剂;硫糖铝

Abstract:

Objective: To observe the effect of the sucralfate and cimetidine on hospital acquired pneumonia in aged esophageal cancer patients. Methods: 176 patients with the age ranging from 60 to 79 were randomly divided into cimetidine group, sucralfate group and comparison group. The hodoromisl pneumonia incidence of the three groups after the esophageal radical operation was observed. Results: The hodoromisl pneumonia incidence of sucialfate cimetidine and comparison groups were 8.6%, 30.7%, 10.7% respectively. Cimetidine group compared to sucralfate and comparison group, there was statistical significant difference, and no statistical significance in sucralfate group compared to comparison group. Conclusion: Sucralfate could probably displace cimetidine in aged postoperative patients with esophageal cancer.

Key words:hodoromisl pneumonia,cimetidine,esophageal cancer,sucralfate