Objective: To evaluate the effect of long-term prognosis and safety about infection remnant pacemaker electrode sealed with silicone adhesive. Methods: 12 inpatient cases which suffered from infections of pacemaker electrode had no effect on repeated dressing change and antibiotics via or through vein infusion and were sealed infection remnant pacemaker electrode with silicone adhesive. After the method was used, the effects were summarized and follow-up materials were analyzed. Results: Among the 12 patients, 11 cases received follow-up. There was no local reinfection, silicone adhesive effusion or endocarditis. The ill upper extremity moved freely. Life qualities were improved significantly. Conclusions: The pacemaker bag infection and damaged skin caused by remnant pacemaker electrode sealed with silicone adhesive is a convenient and useful technique. There are good prospects for applications and popularizations.