Objective: To explore the efficiency of denture stabilizer on lining of complete dentures. Methods: Fifteen cases of alveolus absorbed seriously or denture resented badly or ached at first use of denture with twenty one complete dentures were enrolled in the study. Functions were analyzed after lining complete dentures use of denture stabilizer. Results: Fixation of denture was significantly enhanced, chewing efficiency was improved and the pain of first users was eased. The action of stabilizer could enhance retention and improve chew efficiency and ease the pain of denture users. Conclusion: Dentine stabilizer can enhance fixation of denture and improve chewing efficiency and ease pain of first users.